A well-heeled doctor. An outlaw biker gang. A massive painkiller supply chain.

We aspire to a life without discomfort, without unpleasantness. But what kind of life would that be? It is as hard to imagine a world without pain as a person without sadness: a whole dimension of existence would be missing.

As business declines amidst an opioid epidemic in America, Purdue Pharma’s owners the Sackler family are pursuing a new strategy: putting OxyContin in medicine cabinets around the world.

Purdue Pharma’s marketing materials say OxyContin works for 12 hours. It doesn’t. And this problem, long-denied by the drugmaker, is what makes it highly addictive.

The tragic romance of Jim Irsay, the shrewd owner of the Indianapolis Colts, and Kimberly Wundrum, a mother who shared his longtime addiction to painkillers, that ended with her overdosing in the secret condo he bought her.

How the self-proclaimed “inventor of all things streaming” went from dot-com millionaire to crime ring accomplice.